Biofilm infections have increasingly come into prominence in the past three decades. Acute Infections are bacterial diseases that are caused by planktonic bacterial cells (single cel). Chronic infections are caused by biofilms, multiple microbial species with altered phenotype encased in a protective EPS matrix. Biofilms can form on any surface in the body.
NIH research shows that 80% of infections are caused by Biofilms. Cultures fail to identify the microorganisms in a biofilm phenotype. Microbial DNA sequencing can accurately detect the microorganisms in a biofilm.