Biofilm

“The detection and identification of bacteria present in natural and industrial ecosystems are now entirely based on molecular systems that detect microbial RNA or DNA. Culture methods were abandoned in the 1980s because direct observations showed that less than 1% of the bacteria in these systems grew on laboratory media.”

J.W. CostertonCenter For Genomic Sciences, Father Of Biofilm Research

What is Next Gen Sequencing?

Biofilm infections have increasingly come into prominence in the past three decades. Acute Infections are bacterial diseases that are caused by planktonic bacterial cells (single cel). Chronic infections are caused by biofilms, multiple microbial species with altered phenotype encased in a protective EPS matrix. Biofilms can form on any surface in the body.

NIH research shows that 80% of infections are caused by Biofilms. Cultures fail to identify the microorganisms in a biofilm phenotype. Microbial DNA sequencing can accurately detect the microorganisms in a biofilm.

Read & Watch More About Biofilm

Applications of Clinical Microbial Next-Generation Sequencing

May 2, 2018

Biofilm-Related Periprosthetic 7 Joint Infections

May 2, 2018

ESCMID Guideline for the Diagnosis and Treatment of Biofilm Infections 2014

May 2, 2018

More Effective Cell-Based Therapy Through Biofilm Suppression

May 2, 2018

The Role of Bacterial Biofilms in Chronic Infections

May 2, 2018

ASM Microbe June 2016 Presentation

May 2, 2018

Clinically Addressing Biofilm in Chronic Wounds

May 2, 2018

Culture Negative Infections

May 2, 2018

Molecular Microbiology New Dimensions for Cutaneous Biology and Wound Healing

May 2, 2018

Actionable Diagnosis of Neuroleptospirosis by Next-Generation Sequencing

May 2, 2018

Ramikrishnan Culture vs Sequencing

May 2, 2018

The Problem of Culture-Negative Infections

May 2, 2018

Wolcott Wound Repair and Regeneration

May 2, 2018

Diagnosis of Streptococcus Canis

May 2, 2018

Diagnosis of Streptococcus Canis

May 2, 2018

What Are Bacterial Biofilms?

Dr. Bill Costerton: Diagnosing and Treating Biofilm Infections

Randy Wolcott, MD – Diagnosing & Treating Bacterial Biofilm Infections

Rodney Donlan on Biofilm Infections

Ready to Improve Your Outcomes?