Biofilm

“The detection and identification of bacteria present in natural and industrial ecosystems are now entirely based on molecular systems that detect microbial RNA or DNA. Culture methods were abandoned in the 1980s because direct observations showed that less than 1% of the bacteria in these systems grew on laboratory media.”

J.W. CostertonCenter For Genomic Sciences, Father Of Biofilm Research

What is Next Gen Sequencing?

Biofilm infections have increasingly come into prominence in the past three decades. Acute Infections are bacterial diseases that are caused by planktonic bacterial cells (single cel). Chronic infections are caused by biofilms, multiple microbial species with altered phenotype encased in a protective EPS matrix. Biofilms can form on any surface in the body.

NIH research shows that 80% of infections are caused by Biofilms. Cultures fail to identify the microorganisms in a biofilm phenotype. Microbial DNA sequencing can accurately detect the microorganisms in a biofilm.

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